Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607372 | 0.79 | KDM4E (0.46) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL11870700 | 0.76 | MLYCD (0.48) | L3MBTL1MLYCDMAPTTDP1KMT2A | |
| SCHEMBL31614929 | 0.73 | L3MBTL1 (0.39) | L3MBTL1CA12CA2CA9NR1I2 | |
| SCHEMBL7123604 | 0.72 | KEAP1 (0.46) | L3MBTL1NR1I2SMN1; SMN2TSHR | |
| SCHEMBL6204399 | 0.72 | KEAP1 (0.67) | CA12CA9MAPTKMT2AMEN1 | |
| SCHEMBL14855516 | 0.71 | L3MBTL1 (0.47) | L3MBTL1CA1CA2CA9KDM4E | |
| SCHEMBL8042370 | 0.70 | CES1 (0.42) | L3MBTL1CA1CA2CA9MLYCD | |
| SCHEMBL11754044 | 0.70 | KDM4E (0.54) | L3MBTL1MAPTTDP1KMT2AKDM4E | |
| SCHEMBL20867667 | 0.69 | HSD11B1 (0.53) | L3MBTL1MAPTTDP1KMT2AKDM4E | |
| SCHEMBL6202036 | 0.69 | ADRA2C (0.57) | L3MBTL1MAPTTDP1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001527390-A | — | — | 2001-12-25 | — | — | JP | claimed |
| EP-1011655-A1 | INHIBITORS OF LEADERLESS PROTEIN EXPORT | Ciblex Corporation (US) | 2000-06-28 | — | — | EP | claimed |
| CN-1252716-A | Inhibitors of leaderless protein export | CIBLEX CORP (US) | 2000-05-10 | — | — | CN | claimed |
| WO-1998037880-A1 | INHIBITORS OF LEADERLESS PROTEIN EXPORT | CIBLEX CORPORATION (US) | 1998-09-03 | — | — | WO | claimed |