Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7933100

CC1=C(c2cccc3ccccc23)c2ccccc2C1[Hf+2](C1C(C)=C(c2cccc3ccccc23)c2ccccc21)=[Ge](C)C.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.33
ALDH1A1 P00352 4/20 0.33
CYP2A6 P11509 1/20 0.33
DHFR P00374 1/20 0.32
KDM4E B2RXH2 3/20 0.31
HPGD P15428 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
TDP2 O95551 1/20 0.31
MAPT P10636 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31
HTT P42858 1/20 0.31
GALK1 P51570 1/20 0.31
BLM P54132 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7926729 0.85 ALDH1A1 (0.33) ALDH1A1CYP2A6DHFRKDM4EHPGD
Hydrochloric Acid SCHEMBL7933117 0.84 ALOX5 (0.35) KDM1AALDH1A1KDM4EHPGDL3MBTL1
Hydrochloric Acid SCHEMBL2114523 0.83 DHFR (0.36) KDM1AALDH1A1CYP2A6DHFRKDM4E
Hydrochloric Acid SCHEMBL7926518 0.83 ALOX15 (0.32) KDM1AALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL7212490 0.81 ALDH1A1 (0.33) KDM1AALDH1A1CYP2A6DHFRKDM4E
Hydrochloric Acid SCHEMBL216563 0.81 ENPP3 (0.33) KDM1AALDH1A1CYP2A6DHFRKDM4E
Hydrochloric Acid SCHEMBL4482816 0.81 KDM1A (0.33) KDM1AALDH1A1CYP2A6DHFRKDM4E
Hydrochloric Acid SCHEMBL3765255 0.81 KDM1A (0.33) KDM1AALDH1A1CYP2A6DHFRKDM4E
Hydrochloric Acid SCHEMBL7933040 0.77 ENPP3 (0.32) ALDH1A1CYP2A6DHFRKDM4EHPGD
Hydrochloric Acid SCHEMBL218691 0.76 ENPP3 (0.31) ALDH1A1KDM4EHPGDENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed