Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776274 | 0.86 | CYP2C9 (0.46) | AMY1A | |
| SCHEMBL13840598 | 0.81 | GABRA1 (0.68) | DHFRBACE1GABRA1GABRB2 | |
| SCHEMBL278275 | 0.80 | MAPT (0.45) | — | |
| SCHEMBL2387607 | 0.80 | DHFR (0.54) | DHFRBACE1GABRA1GABRB2AMY1A | |
| SCHEMBL30003843 | 0.80 | DHFR (0.54) | DHFRBACE1GABRA1GABRB2AMY1A | |
| SCHEMBL8963168 | 0.80 | DHFR (0.42) | DHFRBACE1GABRA1GABRB2 | |
| SCHEMBL2475390 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2 | |
| SCHEMBL29719025 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2 | |
| SCHEMBL4364941 | 0.80 | DHFR (0.53) | DHFRBACE1GABRA1GABRB2TRPA1 | |
| SCHEMBL29831656 | 0.79 | SHBG (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245478-B1 | Resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-06-12 | — | — | US | disclosed |