Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990145 | 0.82 | LMNA (0.50) | IDO1PAX8 | |
| SCHEMBL3955098 | 0.80 | IDO1 (0.59) | IDO1GABRA1GABRB2MEN1GAA | |
| SCHEMBL7939589 | 0.80 | DHFR (0.46) | DHFRGABRA1GABRB2BACE1 | |
| SCHEMBL8963163 | 0.79 | LMNA (0.47) | DHFRGABRA1GABRB2 | |
| SCHEMBL3165277 | 0.77 | PAX8 (0.62) | IDO1PAX8MEN1KMT2A | |
| SCHEMBL1397170 | 0.76 | IDO1 (0.65) | IDO1PAX8MEN1KMT2A | |
| SCHEMBL29357437 | 0.76 | IDO1 (0.65) | IDO1PAX8MEN1KMT2A | |
| SCHEMBL13840598 | 0.75 | GABRA1 (0.68) | DHFRGABRA1GABRB2PTPN1PTPN2 | |
| SCHEMBL30003843 | 0.74 | DHFR (0.54) | DHFRGABRA1GABRB2PTPN1PTPN2 | |
| SCHEMBL2387607 | 0.74 | DHFR (0.54) | DHFRGABRA1GABRB2PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543286-A | CONTAINING AN ORGANIC SILVER SALT AND A PYRROLE COMPOUND;HIGH CONTRAST IMAGES | CANON KABUSHIKI KAISHA (JP) | 1996-08-06 | — | — | US | disclosed |
| US-5258281-A | Light sensitive silver halide multilayer elements with dyes and heat development accelerators | CANON KABUSHIKI KAISHA (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0486246-A1 | Heat-developable photosensitive material | CANON KABUSHIKI KAISHA (JP) | 1992-05-20 | — | — | EP | disclosed |