Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946579 | 0.73 | HDAC8 (0.38) | MTNR1AKDM4EALDH1A1 | |
| SCHEMBL28981598 | 0.73 | MTNR1A (0.36) | MTNR1AKDM4EALDH1A1 | |
| SCHEMBL7951889 | 0.72 | KMT2A (0.41) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7948614 | 0.71 | POLB (0.40) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7982554 | 0.71 | SLC6A9 (0.40) | — | |
| SCHEMBL7089442 | 0.71 | HSPA1A (0.45) | SMN1; SMN2MTNR1AKDM4EALDH1A1 | |
| SCHEMBL22864660 | 0.70 | MAPK1 (0.39) | MTNR1A | |
| SCHEMBL7947322 | 0.70 | ALDH1A1 (0.40) | SMN1; SMN2KDM4EALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL7981921 | 0.70 | TSHR (0.40) | SMN1; SMN2KDM4ELMNA | |
| SCHEMBL7946077 | 0.70 | POLB (0.35) | MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |