Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089442 | 0.84 | HSPA1A (0.45) | MTNR1AHTR2CKDM4EALDH1A1 | |
| SCHEMBL22864660 | 0.83 | MAPK1 (0.39) | HDAC8MTNR1AFPR1FPR2 | |
| SCHEMBL28981598 | 0.81 | MTNR1A (0.36) | HDAC8MTNR1AHTR2CKDM4EALDH1A1 | |
| SCHEMBL7951889 | 0.77 | KMT2A (0.41) | KDM4EALDH1A1 | |
| SCHEMBL7982554 | 0.75 | SLC6A9 (0.40) | — | |
| SCHEMBL7948614 | 0.75 | POLB (0.40) | KDM4EALDH1A1 | |
| SCHEMBL7944576 | 0.74 | KCNH2 (0.45) | CHRNB4CHRNA3MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19644392 | 0.73 | SIRT1 (0.43) | HTR2CKDM4EALDH1A1 | |
| SCHEMBL7946424 | 0.73 | SMN1; SMN2 (0.32) | MTNR1AKDM4EALDH1A1 | |
| SCHEMBL7947322 | 0.73 | ALDH1A1 (0.40) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |