Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992034 | 0.97 | F2 (0.33) | CPB2F2BCHECYP2D6SLC6A2 | |
| SCHEMBL7969135 | 0.75 | BCHE (0.38) | F2BCHECYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7986076 | 0.74 | HDAC1 (0.36) | F2BCHECYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7944087 | 0.74 | BCHE (0.37) | BCHECYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7951901 | 0.73 | CTSL (0.32) | CPB2 | |
| SCHEMBL7945088 | 0.73 | HDAC1 (0.38) | F2BCHECYP2D6SLC6A2SLC6A4 | |
| SCHEMBL3124488 | 0.73 | MC4R (0.47) | — | |
| SCHEMBL7947140 | 0.70 | PKM (0.37) | F2CYP2D6 | |
| SCHEMBL3118314 | 0.70 | MC4R (0.48) | — | |
| SCHEMBL3118297 | 0.70 | MC4R (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |