Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948256 | 0.97 | CPB2 (0.36) | F2CPB2BCHEKCNH2CYP2D6 | |
| SCHEMBL7969135 | 0.76 | BCHE (0.38) | F2BCHEKCNH2CYP2D6SLC6A2 | |
| SCHEMBL7951901 | 0.75 | CTSL (0.32) | CPB2 | |
| SCHEMBL7986076 | 0.75 | HDAC1 (0.36) | F2BCHEKCNH2CYP2D6SLC6A2 | |
| SCHEMBL7944087 | 0.75 | BCHE (0.37) | BCHEKCNH2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7945088 | 0.73 | HDAC1 (0.38) | F2BCHEKCNH2CYP2D6SLC6A2 | |
| SCHEMBL3118297 | 0.72 | MC4R (0.48) | — | |
| SCHEMBL3118314 | 0.72 | MC4R (0.48) | — | |
| SCHEMBL7947140 | 0.71 | PKM (0.37) | F2CYP2D6 | |
| SCHEMBL7949797 | 0.70 | F2 (0.34) | F2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |