Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953116 | 0.85 | MAPT (0.47) | ADRB3KMT2A | |
| SCHEMBL7953119 | 0.75 | HTR7 (0.40) | P2RX7 | |
| SCHEMBL7965925 | 0.67 | HTR1A (0.47) | — | |
| SCHEMBL7953252 | 0.64 | CCR2 (0.35) | — | |
| Fumaric Acid SCHEMBL7967350 | 0.62 | RAB9A (0.42) | KMT2A | |
| SCHEMBL7966382 | 0.62 | OPRL1 (0.43) | KMT2A | |
| SCHEMBL16218244 | 0.60 | CYP11B2 (0.57) | — | |
| Pyridine SCHEMBL1270547 | 0.59 | CA1 (0.50) | KMT2A | |
| Pyridine SCHEMBL1270544 | 0.59 | CA1 (0.50) | KMT2A | |
| Alcohol SCHEMBL282185 | 0.59 | CA1 (0.53) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |