Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963764 | 0.79 | MEN1 (0.35) | CCR5DRD3CYP11B2ITGA4ITGB7 | |
| SCHEMBL7965454 | 0.78 | OPRL1 (0.36) | DRD3OPRM1OPRL1HTR1A | |
| SCHEMBL7965779 | 0.78 | ITGA4 (0.33) | CCR5DRD3DRD2CYP11B2CYP11B1 | |
| SCHEMBL8139378 | 0.75 | SLC6A1 (0.34) | CCR5DRD3DRD2CYP11B2OPRM1 | |
| SCHEMBL7963100 | 0.75 | SLC6A1 (0.34) | CCR5DRD3DRD2CYP11B2OPRM1 | |
| SCHEMBL7967096 | 0.74 | TUBB4A (0.38) | CYP11B2CYP11B1OPRM1OPRL1OPRD1 | |
| SCHEMBL7962999 | 0.71 | OPRL1 (0.40) | DRD2OPRM1OPRL1OPRD1HTR1A | |
| SCHEMBL7969481 | 0.71 | LTA4H (0.38) | DRD3DRD2OPRM1OPRL1OPRD1 | |
| SCHEMBL7965995 | 0.71 | — | — | |
| Malonic Acid SCHEMBL7953260 | 0.70 | MAPT (0.44) | HTR1ALMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |