Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13951835 | 0.90 | ANPEP (0.57) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL24850046 | 0.89 | LTB4R (0.48) | ANPEPENPEPALDH1A1KMT2ALTB4R | |
| SCHEMBL12799171 | 0.87 | LMNA (0.43) | ALDH1A1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL23776303 | 0.86 | ANPEP (0.48) | ANPEPENPEPALDH1A1KMT2AGRM4 | |
| SCHEMBL21164506 | 0.86 | PARP1 (0.46) | ANPEPENPEP | |
| SCHEMBL17060017 | 0.83 | MEN1 (0.41) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL6838300 | 0.82 | ANPEP (0.53) | ANPEPENPEPALDH1A1KMT2AGRM4 | |
| SCHEMBL28555690 | 0.82 | ANPEP (0.53) | ANPEPENPEPALDH1A1KMT2AGRM4 | |
| SCHEMBL9843117 | 0.81 | ANPEP (0.59) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| Ammonia Solution, Strong SCHEMBL6014470 | 0.81 | ANPEP (0.51) | ANPEPENPEPALDH1A1KMT2AGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174281-B1 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2021-11-16 | — | — | US | disclosed |
| US-10350208-B2 | Spirocyclic compounds as tryptophan hydroxylase inhibitors | ROIVANT SCIENCES GMBH (CH) | 2019-07-16 | — | — | US | disclosed |
| WO-2001083420-A2 | METHOD OF MAKING SUBSTITUTED DIHALO AROMATIC ACID CHLORIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350208-B2 | Spirocyclic compounds as tryptophan hydroxylase inhibitors | TPH1, TPH2, HTR1A | ANPEP 2262/4885ENPEP 2110/4885ALDH1A1 433/4885 |
| US-11174281-B1 | Modified nucleotides and uses thereof | NUDT1, RNMT, ADAR | ANPEP 880/4885ENPEP 685/4885ALDH1A1 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.