Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485821 | 0.85 | VCP (0.41) | VCPMAOAMAOBCYP11B1CYP11B2 | |
| SCHEMBL7971923 | 0.74 | CHRM5 (0.47) | MAOAMAOB | |
| SCHEMBL7968526 | 0.73 | LMNA (0.40) | CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL7968716 | 0.72 | POLB (0.41) | CYP11B1CYP11B2NPC1RAB9ATDP1 | |
| SCHEMBL8436212 | 0.72 | CYP11B2 (0.39) | MAOBCYP11B1CYP11B2 | |
| SCHEMBL7958255 | 0.71 | NPC1 (0.40) | NPC1RAB9A | |
| SCHEMBL28825690 | 0.70 | GRIN1 (0.42) | — | |
| SCHEMBL28825631 | 0.69 | ALDH1A1 (0.39) | MAOBCYP11B1CYP11B2NPC1 | |
| SCHEMBL7958570 | 0.69 | CYP11B2 (0.46) | CYP11B1CYP11B2NPC1RAB9ATDP1 | |
| SCHEMBL28825579 | 0.69 | NFE2L2 (0.46) | CYP11B1CYP11B2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055703-A1 | 2-ALKYL-3-(HETERO)ARYL-8-AZABICYCLO[3.2.1]ALKANES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |