Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | CCR1 | P32246 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.31 |
| ▸ | DRD4 | P21917 | 4/20 | 0.31 |
| ▸ | DRD3 | P35462 | 4/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 4/20 | 0.30 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
| ▸ | HTR7 | P34969 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953456 | 0.85 | OPRL1 (0.39) | LTA4HOPRL1CCR1OPRM1MEN1 | |
| SCHEMBL7962748 | 0.84 | PDE10A (0.39) | LTA4HOPRL1CCR1MEN1KMT2A | |
| SCHEMBL7962212 | 0.84 | ALDH1A1 (0.41) | OPRL1OPRM1MEN1ALDH1A1LMNA | |
| SCHEMBL7962698 | 0.81 | L3MBTL1 (0.46) | MEN1KMT2A | |
| SCHEMBL7965119 | 0.79 | OPRM1 (0.39) | OPRL1CCR1OPRM1MEN1ALDH1A1 | |
| SCHEMBL7962696 | 0.79 | LTA4H (0.35) | LTA4HOPRL1OPRM1MEN1ALDH1A1 | |
| Sulfuric Acid SCHEMBL7968961 | 0.79 | DRD3 (0.37) | LTA4HDRD2DRD3HTR1A | |
| SCHEMBL7963401 | 0.78 | ADRB2 (0.33) | LTA4HOPRL1OPRM1MEN1LMNA | |
| SCHEMBL7969555 | 0.76 | OPRL1 (0.45) | LTA4HOPRL1CCR1OPRM1MEN1 | |
| SCHEMBL7969312 | 0.75 | LTA4H (0.45) | LTA4HOPRL1CCR1OPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |