Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953682 | 0.87 | ABCB1 (0.47) | LMNAMEN1KMT2ASMN1; SMN2ADRB1 | |
| SCHEMBL7963401 | 0.83 | ADRB2 (0.33) | LMNAMEN1KMT2AADRB1ADRB2 | |
| SCHEMBL7963392 | 0.82 | ADRB2 (0.35) | LMNAMEN1KMT2AADRB1ADRB2 | |
| SCHEMBL7965117 | 0.80 | CYP1A2 (0.58) | LMNAMEN1KMT2ASMN1; SMN2ABCB1 | |
| Fumaric Acid SCHEMBL7966212 | 0.79 | ABCB1 (0.51) | LMNAMEN1KMT2ASMN1; SMN2ABCB1 | |
| SCHEMBL7962698 | 0.78 | L3MBTL1 (0.46) | MEN1KMT2ASMN1; SMN2KDM4ECYP2D6 | |
| SCHEMBL7962210 | 0.77 | TP53 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7964941 | 0.77 | CCR1 (0.45) | LMNAMEN1KMT2ASMN1; SMN2ABCB1 | |
| SCHEMBL7965363 | 0.75 | PRMT5 (0.48) | LMNAMEN1KMT2ASMN1; SMN2ABCB1 | |
| SCHEMBL7962746 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ENPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |