Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953290 | 0.88 | LTA4H (0.38) | PDE10ADRD2DRD3CYP3A4LTA4H | |
| SCHEMBL7962701 | 0.84 | LTA4H (0.36) | DRD2DRD3LTA4HMEN1KMT2A | |
| SCHEMBL7962212 | 0.84 | ALDH1A1 (0.41) | DRD2DRD3MEN1MAPTKMT2A | |
| SCHEMBL7962746 | 0.83 | SMN1; SMN2 (0.47) | PDE10AMAPTHTR1A | |
| SCHEMBL7962985 | 0.82 | LTA4H (0.39) | LTA4HMEN1MAPTKMT2AOPRL1 | |
| SCHEMBL7962741 | 0.81 | PDE10A (0.42) | PDE10ADRD2DRD3CYP3A4MAPT | |
| SCHEMBL7200725 | 0.79 | OPRL1 (0.41) | LTA4HMEN1KMT2AOPRL1CCR1 | |
| Sulfuric Acid SCHEMBL7968961 | 0.79 | DRD3 (0.37) | DRD2DRD3LTA4HHTR1A | |
| SCHEMBL7965119 | 0.78 | OPRM1 (0.39) | DRD2DRD3MEN1MAPTKMT2A | |
| SCHEMBL7969555 | 0.74 | OPRL1 (0.45) | LTA4HMEN1KMT2AOPRL1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |