Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964394 | 0.86 | OPRL1 (0.43) | OPRM1OPRL1OPRD1CYP1A2CYP2D6 | |
| SCHEMBL7965117 | 0.83 | CYP1A2 (0.58) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL7965112 | 0.81 | LMNA (0.39) | OPRM1OPRD1MAPTLMNAKDM4E | |
| SCHEMBL7963401 | 0.80 | ADRB2 (0.33) | OPRM1OPRL1LMNAKDM4EMEN1 | |
| SCHEMBL7962701 | 0.79 | LTA4H (0.36) | OPRM1OPRL1OPRD1LMNAMEN1 | |
| SCHEMBL7962212 | 0.79 | ALDH1A1 (0.41) | OPRM1OPRL1OPRD1MAPTLMNA | |
| SCHEMBL7964943 | 0.79 | LTA4H (0.33) | OPRM1OPRL1CCR1HTR1ADRD2 | |
| SCHEMBL7962748 | 0.78 | PDE10A (0.39) | OPRL1MAPTMEN1KMT2ACCR1 | |
| SCHEMBL7965175 | 0.74 | OPRL1 (0.47) | OPRM1OPRL1CCR1HTR1ADRD2 | |
| Sulfuric Acid SCHEMBL7968961 | 0.72 | DRD3 (0.37) | HTR1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |