Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966053 | 0.86 | MAPT (0.36) | LMNATP53 | |
| Lactic Acid SCHEMBL7966052 | 0.73 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL7966213 | 0.71 | LMNA (0.34) | LMNA | |
| SCHEMBL7966357 | 0.69 | DRD3 (0.38) | — | |
| SCHEMBL7962212 | 0.68 | ALDH1A1 (0.41) | LMNATP53 | |
| SCHEMBL8133875 | 0.67 | DRD3 (0.32) | LMNA | |
| SCHEMBL7965119 | 0.66 | OPRM1 (0.39) | LMNATP53 | |
| Sulfuric Acid SCHEMBL7968961 | 0.65 | DRD3 (0.37) | — | |
| SCHEMBL7962748 | 0.65 | PDE10A (0.39) | — | |
| SCHEMBL7962701 | 0.65 | LTA4H (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |