Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LGMN | Q99538 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15299574 | 0.86 | RORC (0.40) | MMP1HSD11B1CA1CA2MAPT | |
| SCHEMBL4073443 | 0.81 | ALDH1A1 (0.51) | CA1CA2MAPTLGMN | |
| SCHEMBL8429719 | 0.80 | CA1 (0.51) | MMP1CA1CA2 | |
| SCHEMBL2320786 | 0.79 | PSEN1 (0.46) | MMP1HSD11B1CA1CA2 | |
| SCHEMBL4073629 | 0.77 | MMP2 (0.50) | MMP1KIF11MAPTBCHEACHE | |
| SCHEMBL3247012 | 0.76 | ALDH1A1 (0.50) | MMP1HSD11B1CA1CA2CA12 | |
| SCHEMBL12013127 | 0.76 | RORC (0.54) | MMP1KIF11HSD11B1CA1CA2 | |
| SCHEMBL1958962 | 0.75 | KIF11 (0.51) | KIF11CA1CA2CA9RORC | |
| SCHEMBL4074745 | 0.75 | ENPP2 (0.45) | — | |
| SCHEMBL4079205 | 0.75 | F2 (0.41) | MMP1CA1CA2CA12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116675663-A | Preparation method of coumarin compound and application of coumarin compound in neuroprotection | 兰州交通大学 | 2023-09-01 | — | — | CN | claimed |
| WO-2023033890-A1 | NITROGEN-CONTAINING COMPOUNDS AS ADDITIVES FOR SILICON-BASED LI-ION BATTERIES | ENEVATE CORPORATION (US) | 2023-03-09 | — | — | WO | claimed |
| WO-2023033890-A1 | NITROGEN-CONTAINING COMPOUNDS AS ADDITIVES FOR SILICON-BASED LI-ION BATTERIES | ENEVATE CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |
| US-11552334-B1 | Nitrogen-containing compounds as additives for silicon-based Li-ion batteries | ENEVATE CORPORATION (US) | 2023-01-10 | — | — | US | disclosed |
| US-20220024928-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2022-01-27 | — | — | US | disclosed |
| WO-2020109350-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2020-06-04 | — | — | WO | disclosed |
| US-10059713-B2 | 3-substituted 2-amino-indole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-08-28 | — | — | US | disclosed |
| US-9908846-B2 | Composition, synthesis, and use of new arylsulfonyl isonitriles | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170158700-A1 | 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES | TAKEDA CAMBRIDGE LIMITED (GB) | 2017-06-08 | — | — | US | disclosed |
| EP-3160965-A1 | 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2017-05-03 | — | — | EP | disclosed |
| CN-106488919-A | 3-substituted 2-aminoindole derivatives | 武田药品工业株式会社 | 2017-03-08 | — | — | CN | disclosed |
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2015-08-27 | — | — | US | disclosed |
| WO-2013148813-A1 | TRIAZOLOTHIENOPYRIMIDINE COMPOUND INHIBITORS OF UREA TRANSPORTERS AND METHODS OF USING INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-03 | — | — | WO | disclosed |
| US-6225346-B1 | FOR THERAPY AND PROPHYLAXIS OF CELL PROLIFERATIVE DISORDERS OR CELL DIFFERENTIATION DISORDERS ASSOCIATED WITH PARTICULAR TYROSINE KINASES BY INHIBITING ONE OR MORE ABNORMAL TYROSINE KINASE ACTIVITIES | SUGEN, INC. | 2001-05-01 | — | — | US | disclosed |
| US-5935993-A | TYROSINE KINASE INHIBITORS; TREATMENT OF CELL GROWTH, CELL DIFFERENTIATION DISORDERS | SUGEN, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| US-5891917-A | MODULATING TYROSINE SIGNAL TRANSDUCTION TO PREVENT AND TREAT CELL PROLIFERATIVE DISORDERS OR CELL DIFFERENTIATION DISORDERS ASSOCIATED WITH PARTICULAR TYROSINE KINASES BY INHIBITING ONE OR MORE ABNORMAL TYROSINE KINASE ACTIVITIES | SUGEN, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5886195-A | REACTING AN APPROPRIATE CARBOXALDEHYDE WITH AN APPROPRIATE SULFONYLACETONITRILE | SUGEN, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5710173-A | ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS | SUGEN, INC. (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1996040629-A1 | TYRPHOSTIN-LIKE COMPOUNDS FOR THE TREATMENT OF CELL PROLIFERATIVE DISORDERS OR CELL DIFFERENTIATION DISORDERS | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040675-A1 | THIENYL COMPOUNDS FOR INHIBITION OF CELL PROLIFERATIVE DISORDERS | SUGEN, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10059713-B2 | 3-substituted 2-amino-indole derivatives | NPY5R, XDH, NPY4R | MMP1 3287/4885KIF11 3194/4885HSD11B1 2719/4885 |
| US-20220024928-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | OR10J3, ORC3, CBR3 | MMP1 4500/4885KIF11 748/4885HSD11B1 1689/4885 |
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | SRMS, AADAC, CYP3A4 | MMP1 2372/4885KIF11 1442/4885HSD11B1 1720/4885 |
| US-20170158700-A1 | 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES | NPY5R, XDH, NPY4R | MMP1 3287/4885KIF11 3194/4885HSD11B1 2719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.