Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027607 | 0.91 | NQO2 (0.39) | MAPTNQO2ARMEN1KMT2A | |
| SCHEMBL6027636 | 0.86 | ALDH1A1 (0.36) | MAPTNQO2MEN1KMT2ANPC1 | |
| SCHEMBL7971494 | 0.84 | ALDH1A1 (0.33) | MAPTARMEN1KMT2AMAPK1 | |
| SCHEMBL7968407 | 0.82 | POLB (0.46) | MAPTARMEN1KMT2ANPC1 | |
| SCHEMBL7965276 | 0.80 | HSPB1 (0.40) | MAPTARMEN1KMT2ANPC1 | |
| SCHEMBL7968467 | 0.79 | MAPT (0.39) | MAPTARMEN1KMT2ANPC1 | |
| SCHEMBL7971836 | 0.79 | APP (0.49) | MAPTARMEN1KMT2ANPC1 | |
| SCHEMBL2615714 | 0.78 | MAPT (0.55) | MAPTNQO2MEN1KMT2ANPC1 | |
| SCHEMBL6027883 | 0.78 | KDM4E (0.34) | MAPTNQO2MEN1KMT2ANPC1 | |
| SCHEMBL7972386 | 0.77 | MAPT (0.40) | MAPTMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |