Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974709 | 0.77 | NAMPT (0.45) | GRM5NAMPTNFE2L2HTR6 | |
| SCHEMBL7971906 | 0.76 | HTR6 (0.52) | NAMPTACLYPKMFFAR2HTR6 | |
| SCHEMBL7974641 | 0.74 | ALDH1A1 (0.61) | NAMPTPKMHTR6 | |
| SCHEMBL7969060 | 0.70 | GAA (0.55) | NAMPTHTR6 | |
| SCHEMBL7958556 | 0.70 | NAMPT (0.45) | NAMPTHTR6 | |
| SCHEMBL1828079 | 0.69 | HCAR2 (0.42) | NAMPTACLYHTR6 | |
| SCHEMBL7974619 | 0.69 | AKR1B1 (0.47) | NAMPT | |
| SCHEMBL7958946 | 0.69 | KMT2A (0.59) | — | |
| SCHEMBL31097440 | 0.67 | PTGS2 (0.48) | ACLYPTGDR2 | |
| SCHEMBL12417957 | 0.67 | PTGS2 (0.48) | ACLYPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |