Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974641 | 0.87 | ALDH1A1 (0.61) | NAMPTALDH1A1CYP3A4MAPK1PTGS1 | |
| SCHEMBL7969060 | 0.83 | GAA (0.55) | NAMPTALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL7958556 | 0.83 | NAMPT (0.45) | NAMPTALDH1A1CYP3A4MAPK1PTGS1 | |
| SCHEMBL7971906 | 0.82 | HTR6 (0.52) | NAMPTALDH1A1CYP3A4MAPK1HTR6 | |
| SCHEMBL31109058 | 0.79 | HCAR2 (0.54) | NAMPTALDH1A1MAPK1PTGS1PTGS2 | |
| SCHEMBL7974869 | 0.79 | PKM (0.59) | NAMPTNFE2L2 | |
| SCHEMBL7974711 | 0.79 | HCAR2 (0.54) | NAMPTALDH1A1MAPK1PTGS1PTGS2 | |
| SCHEMBL809256 | 0.77 | ALDH1A1 (0.76) | ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL7971616 | 0.77 | GRM5 (0.40) | NAMPTNFE2L2GRM5HTR6 | |
| SCHEMBL3446020 | 0.75 | HSD11B1 (0.57) | NAMPTALDH1A1CYP3A4MAPK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |