Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974641 | 0.83 | ALDH1A1 (0.61) | PKMCA2POLBHTTSMN1; SMN2 | |
| SCHEMBL7969060 | 0.82 | GAA (0.55) | GAARAPGEF4CA2POLBHTT | |
| SCHEMBL4745384 | 0.79 | PKM (0.79) | PKMGAARAPGEF4FFAR4NFE2L2 | |
| SCHEMBL7974709 | 0.79 | NAMPT (0.45) | NFE2L2NAMPT | |
| SCHEMBL7958556 | 0.79 | NAMPT (0.45) | CA2HTTPGRNAMPTLMNA | |
| SCHEMBL7971906 | 0.78 | HTR6 (0.52) | PKMHTTPGRNAMPTLMNA | |
| SCHEMBL13074716 | 0.77 | PKM (1.00) | PKMGAARAPGEF4CA2POLB | |
| SCHEMBL14486413 | 0.77 | PKM (1.00) | PKMGAARAPGEF4CA2POLB | |
| SCHEMBL835692 | 0.77 | PKM (1.00) | PKMGAARAPGEF4CA2POLB | |
| SCHEMBL31109058 | 0.75 | HCAR2 (0.54) | CA2POLBSMN1; SMN2NAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |