Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875636 | 0.83 | NOTUM (0.39) | NOTUMSLC18A3CCR3MEN1KMT2A | |
| SCHEMBL5073795 | 0.78 | MEN1 (0.42) | SLC18A3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1460335 | 0.76 | SMN1; SMN2 (0.37) | SLC18A3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1461471 | 0.75 | NPY1R (0.40) | MEN1KMT2AHRH1KCNH2 | |
| SCHEMBL1462417 | 0.74 | OPRK1 (0.41) | MEN1KMT2AKDM4ERAB9AHTR1A | |
| SCHEMBL1461519 | 0.72 | CBX7 (0.40) | MEN1KMT2AKDM4EALDH1A1RAB9A | |
| Ammonia Solution, Strong SCHEMBL7888875 | 0.72 | KEAP1 (0.47) | KCNQ2MEN1KMT2A | |
| SCHEMBL1460326 | 0.71 | ACHE (0.43) | KDM4E | |
| SCHEMBL1461677 | 0.71 | NCF1 (0.45) | MEN1KMT2AKDM4EALDH1A1HTR1A | |
| SCHEMBL1460361 | 0.71 | LMNA (0.44) | MEN1KMT2ABRD4ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010011091-A1 | Analgesics | ITO FUMITAKA (JP) | 2001-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011091-A1 | Analgesics | OPRL1, OPRK1, OPRD1 | NOTUM 2230/4885KCNQ2 359/4885SLC18A3 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.