Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991370 | 0.85 | KDM4E (0.51) | MAOBALDH1A1KDM4ESMN1; SMN2NR3C2 | |
| SCHEMBL7974168 | 0.84 | CDK9 (0.45) | ROCK2ROCK1MAOBKDM4CALDH1A1 | |
| SCHEMBL7975372 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NR3C2MAPTLMNA | |
| SCHEMBL7974026 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL31333086 | 0.81 | ATM (0.51) | ATMROCK2ROCK1MAOBKCNH2 | |
| SCHEMBL5483136 | 0.80 | PKM (0.59) | ALDH1A1LMNA | |
| SCHEMBL7985070 | 0.80 | P2RY14 (0.48) | ATMKCNH2KDM4CALDH1A1KDM4E | |
| SCHEMBL11491124 | 0.79 | PKM (0.67) | ATMKCNH2KDM4CALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7987445 | 0.79 | PKM (0.57) | ALDH1A1LMNA | |
| SCHEMBL7984239 | 0.78 | ADRA1D (0.52) | ROCK2ROCK1NR3C2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |