Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989347 | 0.86 | CYP11B1 (0.44) | ALDH1A1CYP11B1CYP11B2LMNAADRA1D | |
| SCHEMBL7974168 | 0.84 | CDK9 (0.45) | ALDH1A1CYP11B1CYP11B2TSHRSMN1; SMN2 | |
| SCHEMBL7974026 | 0.84 | KDM4E (0.58) | ALDH1A1CYP11B1CYP11B2LMNAADRA1D | |
| SCHEMBL7988093 | 0.84 | FYN (0.43) | TSHRGAAPKMKMT2A | |
| SCHEMBL7984239 | 0.84 | ADRA1D (0.52) | LMNAADRA1DADORA2AADORA1TP53 | |
| SCHEMBL7988530 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1CYP11B1CYP11B2LMNACYP1A2 | |
| SCHEMBL5483136 | 0.83 | PKM (0.59) | ALDH1A1CYP11B1CYP11B2LMNAADRA1D | |
| Hydrochloric Acid SCHEMBL7987445 | 0.82 | PKM (0.57) | ALDH1A1CYP11B1CYP11B2LMNAADRA1D | |
| SCHEMBL7974034 | 0.81 | ATM (0.48) | ALDH1A1LMNASMN1; SMN2TP53MAPT | |
| SCHEMBL7987961 | 0.80 | MAPT (0.47) | ALDH1A1CYP11B1CYP11B2LMNAADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |