Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987961 | 0.86 | MAPT (0.47) | KMT2AYTHDC1ALDH1A1MAPTPKM | |
| SCHEMBL7985670 | 0.85 | CDK9 (0.42) | KMT2AYTHDC1ALDH1A1MAPTKDM4E | |
| SCHEMBL7974162 | 0.85 | KDM4E (0.52) | KMT2AYTHDC1ALDH1A1FGFR1FGFR4 | |
| SCHEMBL7991565 | 0.84 | TSHR (0.49) | KMT2AYTHDC1ALDH1A1GAAFGFR1 | |
| SCHEMBL7992368 | 0.83 | TP53 (0.47) | KMT2AYTHDC1MTNR1AMTNR1BMAPT | |
| SCHEMBL7988093 | 0.81 | FYN (0.43) | KMT2AYTHDC1GAAPLK1HDAC1 | |
| SCHEMBL7987598 | 0.81 | RIOK2 (0.41) | KMT2AYTHDC1ALDH1A1JAK3FGFR1 | |
| SCHEMBL7985495 | 0.79 | CYP11B1 (0.39) | KMT2AYTHDC1FGFR1FGFR4MAPT | |
| SCHEMBL7973987 | 0.79 | FGFR1 (0.45) | KMT2AGAAHDAC1HDAC6FGFR1 | |
| SCHEMBL7985508 | 0.79 | ALDH1A1 (0.43) | KMT2AALDH1A1CACNA1HMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |