Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977571 | 0.86 | NPC1 (0.53) | MAPK1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7977564 | 0.84 | POLB (0.50) | ALDH1A1MAPK1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7980318 | 0.81 | HPGD (0.51) | ALDH1A1MAPK1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL7980366 | 0.81 | NPSR1 (0.63) | ALDH1A1MAPK1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7977544 | 0.80 | LMNA (0.57) | KMT2ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL7974413 | 0.80 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL7974434 | 0.78 | POLB (0.65) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL7980306 | 0.77 | NPSR1 (0.49) | RAB9ANPC1NPSR1GAA | |
| SCHEMBL7975405 | 0.77 | MAPT (0.54) | ALDH1A1KMT2ATP53SMN1; SMN2MAPT | |
| SCHEMBL7977587 | 0.77 | NPC1 (0.58) | ALDH1A1KMT2ASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |