Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 8/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974340 | 0.81 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL7972863 | 0.77 | HRH3 (0.46) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL7961186 | 0.77 | HTR1A (0.43) | DRD2DRD3 | |
| SCHEMBL7359992 | 0.77 | LMNA (0.49) | — | |
| SCHEMBL7977073 | 0.76 | SIGMAR1 (0.44) | — | |
| SCHEMBL7972868 | 0.74 | HRH3 (0.41) | — | |
| SCHEMBL7973158 | 0.72 | MEN1 (0.46) | — | |
| SCHEMBL7972674 | 0.71 | MEN1 (0.49) | DRD2 | |
| SCHEMBL7974462 | 0.69 | MAPT (0.47) | — | |
| SCHEMBL8438174 | 0.69 | CHRNB2 (0.78) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |