Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975372 | 0.84 | ALDH1A1 (0.51) | GAAPKMTSHRKMT2A | |
| SCHEMBL7986281 | 0.81 | KMT2A (0.39) | PLK1GAAPKMTSHRHDAC1 | |
| SCHEMBL7974168 | 0.81 | CDK9 (0.45) | GAAPKMTSHRL3MBTL1 | |
| SCHEMBL7974026 | 0.81 | KDM4E (0.58) | GAAPKMTSHRYTHDC1KDM4E | |
| SCHEMBL7984239 | 0.81 | ADRA1D (0.52) | YTHDC1KMT2A | |
| SCHEMBL5483136 | 0.80 | PKM (0.59) | GAAPKMTSHR | |
| Hydrochloric Acid SCHEMBL7987445 | 0.79 | PKM (0.57) | GAAPKMTSHR | |
| SCHEMBL7974034 | 0.78 | ATM (0.48) | KDM4E | |
| SCHEMBL7987490 | 0.76 | ADORA2A (0.44) | GAAPKMTSHRKMT2A | |
| SCHEMBL7987245 | 0.75 | ROCK2 (0.47) | FYNHDAC1HDAC6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |