Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980528 | 0.83 | PKM (0.33) | OXTRAVPR1APKM | |
| SCHEMBL7985830 | 0.81 | POLB (0.34) | ALDH1A1OXTRAVPR1ALMNATDP1 | |
| SCHEMBL7980536 | 0.81 | PTGDR2 (0.35) | OXTRAVPR1APKMRAB9A | |
| SCHEMBL7982833 | 0.80 | PKM (0.33) | OXTRAVPR1APKMRAB9A | |
| SCHEMBL7969219 | 0.80 | KMT2A (0.34) | OXTRAVPR1APKMKLK7TDP1 | |
| SCHEMBL7979149 | 0.77 | NPC1 (0.39) | ALDH1A1NPSR1RAB9A | |
| SCHEMBL7982224 | 0.77 | RAB9A (0.34) | ALDH1A1PKMNPSR1RAB9A | |
| SCHEMBL7969240 | 0.75 | ALDH1A1 (0.36) | ALDH1A1LMNANPSR1RAB9A | |
| SCHEMBL7979470 | 0.75 | MAPK1 (0.36) | ALDH1A1ACKR3NPSR1RAB9A | |
| SCHEMBL7946315 | 0.74 | MAPK14 (0.36) | ALDH1A1OXTRAVPR1APKMDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |