Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947177 | 0.88 | MAPT (0.50) | ALDH1A1MAPTL3MBTL1ROCK2ROCK1 | |
| SCHEMBL7938686 | 0.83 | ALDH1A1 (0.40) | MAPK14ALDH1A1PKMROCK2ROCK1 | |
| SCHEMBL4306639 | 0.83 | MAPK14 (0.37) | MAPK14ALDH1A1PKMMAPTL3MBTL1 | |
| SCHEMBL7982425 | 0.82 | PKM (0.43) | MAPK14ALDH1A1PKMMAPTL3MBTL1 | |
| SCHEMBL4315205 | 0.81 | POLB (0.37) | MAPK14ALDH1A1PKMMAPTL3MBTL1 | |
| SCHEMBL3120950 | 0.81 | ALDH1A1 (0.40) | MAPK14ALDH1A1PKMMAPTL3MBTL1 | |
| SCHEMBL4304078 | 0.80 | MAPK14 (0.43) | MAPK14ALDH1A1PKMMAPTL3MBTL1 | |
| SCHEMBL4310271 | 0.80 | ALDH1A1 (0.41) | MAPK14ALDH1A1MAPTL3MBTL1ROCK2 | |
| SCHEMBL3263677 | 0.79 | GABRA1 (0.45) | MAPK14ALDH1A1PKMMAPT | |
| SCHEMBL3121013 | 0.77 | ALDH1A1 (0.40) | MAPK14ALDH1A1PKMMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |