SCHEMBL7980848

SCHEMBL7980848

[c]1oc2ccccc2c1-c1[nH]cc2ccccc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1672648 0.73 ALDH1A1 (0.43)
SCHEMBL6256201 0.70 MAPT (0.44) MAOB
SCHEMBL8443578 0.70 MAOB (0.46) MAOB
SCHEMBL3685297 0.69 ADRA2A (0.45)
SCHEMBL7808907 0.69 KDM4E (0.42)
SCHEMBL2958656 0.69 CA1 (0.36)
SCHEMBL5567669 0.68 KDM4E (0.36)
SCHEMBL1018789 0.68 ALOX5 (0.46) MAOB
SCHEMBL7186438 0.68 ATM (0.32)
SCHEMBL931606 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313117-B1 TREATING AUTOIMMUNE DISORDERS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2001-11-06 US claimed
CN-112996800-B Novel proteolytically targeted chimeras (PROTAC) and derivatives thereof as SMARCA2 and/or SMARCA4 degrading agents 勃林格殷格翰国际有限公司 2024-06-25 CN disclosed
CN-109748901-B Condensed cyclic compound and organic light-emitting device including the same 三星显示有限公司 2024-04-23 CN disclosed
CN-111741954-B Novel benzimidazole compounds and derivatives as EGFR inhibitors 勃林格殷格翰国际有限公司 2024-04-02 CN disclosed
CN-114007698-B Macrocyclic compounds and derivatives as EGFR inhibitors 勃林格殷格翰国际有限公司 2024-01-09 CN disclosed
CN-111163775-B Novel [1,6] naphthyridine compounds and derivatives as CDK8/CDK19 inhibitors 勃林格殷格翰国际有限公司 2023-07-11 CN disclosed
CN-116234806-A Cyclic 2-amino-3-cyanothiophenes and derivatives thereof for the treatment of cancer 勃林格殷格翰国际有限公司 2023-06-06 CN disclosed