Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798212 | 0.91 | MEN1 (0.65) | ACHETRPV1PTGS1ABCG2 | |
| SCHEMBL797771 | 0.89 | TRPV1 (0.68) | ACHETRPV1PTGS1PTGS2ABCG2 | |
| SCHEMBL31277254 | 0.83 | ACHE (0.75) | ACHETRPV1PTGS1PTGS2SNCA | |
| SCHEMBL5342883 | 0.83 | ACHE (0.75) | ACHETRPV1PTGS1PTGS2SNCA | |
| SCHEMBL15151730 | 0.83 | TRPV1 (0.60) | ACHETRPV1PTGS1PTGS2ABCG2 | |
| SCHEMBL10071693 | 0.80 | TYR (0.81) | ACHETRPV1PTGS1PTGS2KDM4E | |
| SCHEMBL8802846 | 0.79 | TRPM8 (0.68) | ACHETRPV1PTGS1PTGS2TRPM8 | |
| SCHEMBL794173 | 0.78 | TYR (0.70) | ACHETRPV1PTGS1PTGS2KDM4E | |
| SCHEMBL7019674 | 0.77 | ACHE (0.66) | ACHETRPV1PTGS1PTGS2SNCA | |
| Methylene Chloride SCHEMBL29157543 | 0.77 | TRPM8 (0.64) | ACHETRPV1PTGS1PTGS2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616439-B1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | COUNCIL SCIENT IND RES (IN) | 2015-12-16 | — | — | EP | claimed |
| US-8901317-B2 | Tryptamine derivatives, their preparation and their use in gastropathy | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-02 | — | — | US | claimed |
| EP-2616439-B1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | COUNCIL SCIENT IND RES (IN) | 2015-12-16 | — | — | EP | disclosed |
| US-8901317-B2 | Tryptamine derivatives, their preparation and their use in gastropathy | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-02 | — | — | US | disclosed |
| US-20130197052-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | UNIVERSITY OF CALCUTTA (IN) | 2013-08-01 | — | — | US | disclosed |
| EP-2616439-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | Council of Scientific & Industrial Research (IN) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035406-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197052-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | HTRA2, AIFM1, SI | ACHE 1333/4885TRPV1 253/4885PTGS1 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.