Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981085 | 0.85 | CA12 (0.34) | — | |
| SCHEMBL7981155 | 0.85 | NR3C2 (0.33) | TACR1 | |
| SCHEMBL7992900 | 0.83 | PTGIR (0.33) | — | |
| SCHEMBL7938183 | 0.83 | ALDH1A1 (0.37) | TACR1 | |
| SCHEMBL7980536 | 0.79 | PTGDR2 (0.35) | SLC6A9 | |
| SCHEMBL3906901 | 0.76 | PRKAB2 (0.39) | — | |
| SCHEMBL7980506 | 0.75 | GAA (0.42) | — | |
| SCHEMBL7982833 | 0.75 | PKM (0.33) | — | |
| SCHEMBL7981280 | 0.73 | PIN1 (0.40) | — | |
| SCHEMBL22864635 | 0.71 | SLC6A3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |