Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998218 | 0.93 | SLC29A1 (0.46) | SLC29A1CYP3A4CYP2D6OPRK1P2RX7 | |
| SCHEMBL7983855 | 0.89 | SLC29A1 (0.36) | SLC29A1CYP3A4CYP2D6OPRK1P2RX7 | |
| SCHEMBL7983856 | 0.86 | P2RX7 (0.39) | SLC29A1CYP3A4CYP2D6OPRK1P2RX7 | |
| SCHEMBL7997538 | 0.77 | ALDH1A1 (0.47) | P2RX7BRD4LMNABRD9HSP90AA1 | |
| SCHEMBL7998436 | 0.76 | CYP3A4 (0.42) | CYP3A4CYP2D6OPRK1CYP2C19LMNA | |
| SCHEMBL7983691 | 0.74 | LMNA (0.38) | SLC29A1CYP3A4CYP2D6OPRK1CYP2C19 | |
| SCHEMBL7984571 | 0.71 | CYP3A4 (0.43) | CYP3A4CYP2D6OPRK1CYP2C19LMNA | |
| SCHEMBL8001778 | 0.70 | F2 (0.33) | CYP3A4CYP2D6OPRK1CYP2C19LMNA | |
| SCHEMBL7998028 | 0.70 | TBXAS1 (0.48) | P2RX7BRD4BRD9 | |
| SCHEMBL7997717 | 0.70 | NPSR1 (0.47) | CYP3A4CYP2D6OPRK1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |