Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | MELK | Q14680 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984937 | 0.92 | ADORA3 (0.52) | CDC7DAPK3PAK4CDK2FLT3 | |
| SCHEMBL7974029 | 0.91 | ADORA3 (0.50) | HDAC3HDAC1HDAC2HDAC8KMT2A | |
| SCHEMBL7988231 | 0.88 | NPC1 (0.47) | HDAC3HDAC1HDAC2HDAC8CDK5 | |
| SCHEMBL7985340 | 0.88 | NTRK1 (0.51) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7973996 | 0.87 | POLB (0.49) | HDAC1HDAC8CDC7DAPK3PAK4 | |
| SCHEMBL7992192 | 0.86 | HSD17B13 (0.46) | HDAC1HDAC2CDK2KMT2AMEN1 | |
| SCHEMBL7975241 | 0.85 | GAA (0.50) | HDAC3HDAC1HDAC2HDAC8FLT3 | |
| SCHEMBL7984965 | 0.85 | ALDH1A1 (0.57) | KMT2AMEN1CASP3SENP8SENP7 | |
| SCHEMBL7974318 | 0.83 | HSD17B13 (0.43) | HDAC3HDAC1HDAC2HDAC8FLT3 | |
| SCHEMBL7984687 | 0.82 | NR1H4 (0.52) | KMT2AMEN1MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |