Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984687 | 0.92 | NR1H4 (0.52) | ALDH1A1NR1H4POLBMAPTKMT2A | |
| SCHEMBL7984937 | 0.91 | ADORA3 (0.52) | ALDH1A1LMNAHTTNPC1RAB9A | |
| SCHEMBL7974205 | 0.90 | NR1H4 (0.52) | ALDH1A1NR1H4KMT2AMEN1 | |
| SCHEMBL7985033 | 0.86 | NLRP3 (0.46) | ALDH1A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7975241 | 0.85 | GAA (0.50) | LMNANPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7985340 | 0.85 | NTRK1 (0.51) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7974265 | 0.85 | MCHR1 (0.47) | LMNAHTTNPC1RAB9APOLB | |
| SCHEMBL7984492 | 0.85 | ADORA2A (0.53) | ALDH1A1KDM4E | |
| SCHEMBL7984200 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7987486 | 0.82 | KDM4E (0.48) | LMNASMN1; SMN2KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |