Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984687 | 0.96 | NR1H4 (0.52) | NR1H4SMPD1ALDH1A1MEN1KMT2A | |
| SCHEMBL7984965 | 0.90 | ALDH1A1 (0.57) | NR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL7984937 | 0.87 | ADORA3 (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7987486 | 0.82 | KDM4E (0.48) | MEN1KMT2A | |
| SCHEMBL7985340 | 0.81 | NTRK1 (0.51) | MEN1KMT2A | |
| SCHEMBL7974265 | 0.81 | MCHR1 (0.47) | MEN1KMT2A | |
| SCHEMBL7973996 | 0.78 | POLB (0.49) | SMPD1ALDH1A1MEN1KMT2A | |
| SCHEMBL7988231 | 0.78 | NPC1 (0.47) | KMT2A | |
| SCHEMBL7974040 | 0.78 | KDM4E (0.51) | ALDH1A1 | |
| SCHEMBL7987935 | 0.78 | XDH (0.47) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |