Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991669 | 0.93 | HDAC1 (0.38) | CDK9ROCK2ROCK1EPHX2PPARG | |
| SCHEMBL7991635 | 0.90 | IDO1 (0.37) | CDK9ROCK2ROCK1EPHX2PPARG | |
| SCHEMBL7974416 | 0.90 | MET (0.43) | MAPK14HSD17B13KDM4EMEN1ALDH1A1 | |
| SCHEMBL7985791 | 0.90 | CYP11B1 (0.40) | CDK9EPHX2PPARGHSD17B13BRD4 | |
| SCHEMBL7984659 | 0.89 | ALDH1A1 (0.44) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7985360 | 0.88 | POLB (0.40) | CDK9L3MBTL1HSD17B13LMNAHDAC6 | |
| SCHEMBL7987253 | 0.88 | HPGDS (0.40) | ALDH1A1HPGDCYP11B1CYP11B2ADORA2A | |
| Hydrochloric Acid SCHEMBL7987662 | 0.88 | ALDH1A1 (0.43) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7988638 | 0.88 | MET (0.42) | CDK9ROCK2ROCK1MAPK14EPHX2 | |
| SCHEMBL7991557 | 0.87 | LMNA (0.43) | SLC2A1KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |