Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991980 | 0.86 | MAOB (0.51) | KDM4ELMNASMN1; SMN2MAPK14CYP1A2 | |
| SCHEMBL7986965 | 0.80 | MAPT (0.41) | LMNASMN1; SMN2MAPK14CYP1A2CYP2C9 | |
| SCHEMBL7986045 | 0.76 | MEN1 (0.40) | MAPK14MAPTL3MBTL1 | |
| SCHEMBL7989153 | 0.74 | ALDH1A1 (0.43) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7985834 | 0.74 | MEN1 (0.43) | SMN1; SMN2MAPK14MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7974745 | 0.72 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL7975567 | 0.71 | MAPK14 (0.49) | MAPK14SCN9AMAPTL3MBTL1IKBKB | |
| SCHEMBL7988190 | 0.68 | PDE10A (0.45) | MAPK14CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL5619727 | 0.68 | CYP19A1 (0.44) | KDM4ELMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL4315032 | 0.68 | CA12 (0.73) | KDM4ELMNACA12CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | disclosed |