Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984755 | 0.84 | LMNA (0.56) | ACP1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL7987743 | 0.82 | SCD (0.50) | ACP1TSHRCYP2C19HTTCYP2C9 | |
| SCHEMBL7974026 | 0.79 | KDM4E (0.58) | ACP1TSHRHTTMAPK1SMN1; SMN2 | |
| SCHEMBL7989385 | 0.77 | PPARG (0.47) | ACP1CYP2D6TSHRCYP1A2CYP3A4 | |
| SCHEMBL7974058 | 0.76 | TNF (0.50) | TSHRCYP2C19HTTCYP1A2CYP3A4 | |
| SCHEMBL5483136 | 0.75 | PKM (0.59) | ACP1TSHRALDH1A1 | |
| SCHEMBL21121703 | 0.74 | ACP1 (0.47) | ACP1CYP2D6TSHRCYP2C19HTT | |
| Hydrochloric Acid SCHEMBL7987445 | 0.73 | PKM (0.57) | ACP1TSHRALDH1A1 | |
| SCHEMBL7984782 | 0.73 | ALDH1A1 (0.43) | PPARGMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7988530 | 0.72 | SMN1; SMN2 (0.46) | TSHRCYP2C19HTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |