Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437727 | 0.80 | MAPT (0.48) | MAPTACHEHSD17B10RAB9APOLB | |
| SCHEMBL29580092 | 0.76 | MAPT (0.50) | MAPTRAB9APOLBALDH1A1CYP1A2 | |
| SCHEMBL10936934 | 0.76 | MAPT (0.50) | MAPTRAB9APOLBALDH1A1CYP1A2 | |
| SCHEMBL27803434 | 0.76 | MAPT (0.49) | MAPTRAB9APOLBLMNANPC1 | |
| SCHEMBL14191937 | 0.75 | CCR1 (0.41) | MAPTHSD17B10RAB9ACCR1CCR5 | |
| SCHEMBL17262089 | 0.74 | MAPT (0.47) | MAPTRAB9APOLBALDH1A1LMNA | |
| SCHEMBL12426895 | 0.74 | MAPT (0.47) | MAPTRAB9APOLBALDH1A1LMNA | |
| SCHEMBL135841 | 0.74 | MAPT (0.47) | MAPTRAB9APOLBALDH1A1CYP1A2 | |
| SCHEMBL169463 | 0.74 | MAPT (0.47) | MAPTRAB9APOLBKMT2A | |
| SCHEMBL18617604 | 0.74 | MAPT (0.47) | MAPTRAB9APOLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040446-A | CDK inhibitors | 基因泰克公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |
| CN-111377934-B | Heterocyclic compound, preparation and application thereof | 中国科学院上海药物研究所 | 2023-01-24 | — | — | CN | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| US-20220296595-A1 | CDK INHIBITORS | GENENTECH, INC. | 2022-09-22 | — | — | US | disclosed |
| CN-114364675-A | CDK inhibitors | 上海齐鲁锐格医药研发有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-3966213-A1 | CDK INHIBITORS | Qilu Regor Therapeutics Inc. (CN) | 2022-03-16 | — | — | EP | disclosed |
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |
| CN-111377934-A | Heterocyclic compound, preparation and application thereof | 中国科学院上海药物研究所 | 2020-07-07 | — | — | CN | disclosed |
| WO-2011147259-A1 | NOVEL BENZOXAZINE OXAZOLIDINONE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | 中国科学院上海药物研究所 (CN) | 2011-12-01 | — | — | WO | disclosed |
| US-20110124651-A1 | FLUORINE-CONTAINING ORGANOSULFUR COMPOUND AND PESTICIDAL COMPOSITION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20110124651-A1 | FLUORINE-CONTAINING ORGANOSULFUR COMPOUND AND PESTICIDAL COMPOSITION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED. (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20110027178-A1 | IMAGING THE CENTRAL NERVOUS SYSTEM | GE HEALTHCARE LIMITED (GB) | 2011-02-03 | — | — | US | disclosed |
| US-20110027178-A1 | IMAGING THE CENTRAL NERVOUS SYSTEM | GE HEALTHCARE LIMITED (GB) | 2011-02-03 | — | — | US | disclosed |
| US-20070066631-A1 | Pyrazolyl substituted xanthines | ADENOSINE THERAPEUTICS, LLC | 2007-03-22 | — | — | US | disclosed |
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-4778896-A | Process for the preparation of 5-chloromethylpyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0260485-A1 | Process for the preparation of 2-chlor-5-chloromethyl pyridine | BAYER AG (DE) | 1988-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066631-A1 | Pyrazolyl substituted xanthines | ADORA2B, ADORA2A, ADORA3 | MAPT 4515/4885ACHE 2564/4885HSD17B10 2788/4885 |
| US-20110124651-A1 | FLUORINE-CONTAINING ORGANOSULFUR COMPOUND AND PESTICIDAL COMPOSITION THEREOF | DDT, AFF1, Q6ZSR9 | MAPT 4159/4885ACHE 70/4885HSD17B10 1559/4885 |
| US-20110027178-A1 | IMAGING THE CENTRAL NERVOUS SYSTEM | P2RX3, P2RX7, P2RX2 | MAPT 1227/4885ACHE 1422/4885HSD17B10 3668/4885 |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | PDXK, HIPK1, PCK1 | MAPT 3895/4885ACHE 4806/4885HSD17B10 603/4885 |
| US-20220296595-A1 | CDK INHIBITORS | CDKL1, CDK9, CDK6 | MAPT 2167/4885ACHE 4735/4885HSD17B10 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.