Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985830 | 0.91 | POLB (0.34) | ALDH1A1ROCK2POLBMAPT | |
| SCHEMBL7948016 | 0.79 | POLB (0.38) | ALDH1A1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7947164 | 0.78 | PLA2G2A (0.37) | ALDH1A1L3MBTL1SLC2A1MEN1KMT2A | |
| SCHEMBL7938360 | 0.78 | POLB (0.36) | ALDH1A1L3MBTL1SLC2A1MEN1KMT2A | |
| SCHEMBL7948614 | 0.77 | POLB (0.40) | ALDH1A1L3MBTL1POLBNPC1MAPT | |
| SCHEMBL7945107 | 0.77 | POLB (0.36) | ALDH1A1L3MBTL1SLC2A1POLBNPC1 | |
| SCHEMBL4310162 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AROCK2 | |
| SCHEMBL7946077 | 0.76 | POLB (0.35) | ALDH1A1L3MBTL1SLC2A1MEN1KMT2A | |
| SCHEMBL7969073 | 0.76 | MTNR1B (0.35) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7946743 | 0.76 | MITF (0.45) | ALDH1A1L3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |