SCHEMBL279954

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL680561	0.89	MMP13 (0.65)	HDAC1HDAC6ALDH1A1GAASCN9A
	SCHEMBL29765489	0.82	HDAC1 (0.61)	HDAC1HDAC6ALDH1A1GAANPC1
	SCHEMBL22097521	0.82	SCN9A (0.54)	HDAC1HDAC6SCN9AP4HTMPTPN1
	SCHEMBL7987812	0.82	SCN9A (0.55)	GAASCN9AP4HTMPTGS2MEN1
	SCHEMBL7118965	0.82	ALDH1A1 (0.58)	HDAC1HDAC6ALDH1A1SCN9AP4HTM
	SCHEMBL3374779	0.82	SCN9A (0.54)	ALDH1A1SCN9ANPC1RAB9AP4HTM
	SCHEMBL9913954	0.82	KMT2A (0.54)	ALDH1A1GAASCN9ANPC1RAB9A
	SCHEMBL7990845	0.82	FLT1 (0.65)	ALDH1A1SCN9AP4HTMPTGS2LMNA
	SCHEMBL1647742	0.82	LMNA (0.54)	ALDH1A1SCN9ANPC1RAB9AP4HTM
	SCHEMBL364110	0.81	HDAC3 (0.58)	HDAC1HDAC6ALDH1A1GAASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.