Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 11/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995089 | 0.79 | HTT (0.54) | CALM1MAOBHTTL3MBTL1 | |
| SCHEMBL9771763 | 0.74 | CALM1 (0.69) | CALM1IDO1KDM4E | |
| SCHEMBL7998680 | 0.73 | HTT (0.48) | HTT | |
| SCHEMBL7998683 | 0.72 | HTT (0.53) | MAOBBCHEHTT | |
| SCHEMBL7992008 | 0.72 | HTT (0.47) | MAOBHTTL3MBTL1KDM4E | |
| SCHEMBL7995327 | 0.71 | HTT (0.46) | HTT | |
| SCHEMBL7995324 | 0.69 | HTT (0.55) | MAOBHTTL3MBTL1 | |
| SCHEMBL8680676 | 0.67 | ALOX5 (0.61) | CALM1IDO1KDM4E | |
| SCHEMBL10470441 | 0.66 | ALDH1A1 (0.62) | CALM1IDO1HTTKDM4E | |
| SCHEMBL5940740 | 0.64 | HTR1A (0.54) | L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009129-A2 | 1H-PIRIDO[3, 4-B]INDOL-1-ONE DERIVATIVES | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |