Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19065135 | 0.80 | BCAT2 (0.44) | MEN1RAB9AKMT2AALDH1A1CHRNB2 | |
| SCHEMBL10599404 | 0.80 | HSP90AA1 (0.46) | HDAC1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7392337 | 0.73 | SIGMAR1 (0.40) | RAB9AHSD17B10ALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL10969933 | 0.73 | ALDH1A1 (0.44) | MEN1TP53RAB9AKMT2AHSD17B10 | |
| SCHEMBL16936095 | 0.71 | CHRNB2 (0.49) | TP53KMT2AALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL610542 | 0.70 | L3MBTL1 (0.45) | HDAC1HDAC7HDAC8HDAC6MEN1 | |
| SCHEMBL8187332 | 0.70 | TDO2 (0.38) | HDAC8HDAC6MEN1RAB9AKMT2A | |
| SCHEMBL4056504 | 0.69 | ALDH1A1 (0.41) | HDAC8HDAC6MEN1KMT2AHSD17B10 | |
| SCHEMBL8755361 | 0.68 | RAB9A (0.71) | HDAC1HDAC7HDAC8HDAC6MEN1 | |
| SCHEMBL474941 | 0.67 | HDAC1 (0.65) | HDAC1HDAC7HDAC8HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087852-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL URACILS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |