Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.55 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984832 | 0.91 | PTGES (0.63) | PTGESSGMS2MEN1KMT2ABRD4 | |
| SCHEMBL7994940 | 0.88 | PTGES (0.52) | PTGESPRKDCIKBKBSGMS2PIK3CD | |
| SCHEMBL7996440 | 0.83 | PTGES (0.54) | PTGESNPSR1PIK3CDMEN1NPC1 | |
| SCHEMBL7994971 | 0.83 | PTGES (0.59) | PTGESPRKDCABCB1PIK3CDBRD4 | |
| SCHEMBL7984763 | 0.81 | PTGES (0.54) | PTGESNPSR1MEN1NPC1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7996801 | 0.80 | PTGES (0.52) | PTGESPRKDCIKBKBSGMS2PIK3CD | |
| SCHEMBL7984591 | 0.78 | PTGES (0.61) | PTGESTTRMEN1NPC1KMT2A | |
| SCHEMBL7996719 | 0.77 | PTGES (0.64) | PTGESMEN1KMT2ARAB9APIM1 | |
| SCHEMBL7994951 | 0.73 | PTGES (0.56) | PTGESTTRNPSR1MEN1KMT2A | |
| SCHEMBL8338946 | 0.71 | TTK (0.50) | PRKDCABCB1IKBKBSGMS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |