Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984832 | 0.82 | PTGES (0.63) | PTGESMEN1KMT2ALMNAMAPT | |
| SCHEMBL7996575 | 0.81 | PTGES (0.55) | PTGESMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7994971 | 0.80 | PTGES (0.59) | PTGESKCNA3 | |
| SCHEMBL7996440 | 0.80 | PTGES (0.54) | PTGESMEN1KMT2AKDM4EMAPT | |
| SCHEMBL7994940 | 0.78 | PTGES (0.52) | PTGESALDH1A1POLB | |
| SCHEMBL7984591 | 0.77 | PTGES (0.61) | PTGESMEN1KMT2AKDM4EMAPT | |
| SCHEMBL7996719 | 0.76 | PTGES (0.64) | PTGESMEN1KMT2ALMNAKDM4E | |
| SCHEMBL7994861 | 0.75 | PTGES (0.59) | PTGESMEN1KMT2AMAPTBLM | |
| SCHEMBL7994951 | 0.73 | PTGES (0.56) | PTGESMEN1KMT2ALMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL7996801 | 0.71 | PTGES (0.52) | PTGESMAPTSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |