Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.51 |
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997433 | 0.88 | ALDH1A1 (0.52) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL7983893 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL7963947 | 0.75 | RAB9A (0.70) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL12503286 | 0.68 | FKBP1A (0.71) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL7994038 | 0.68 | HTR7 (0.33) | — | |
| SCHEMBL24893070 | 0.68 | L3MBTL1 (0.53) | ALDH1A1TSHRL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9529304 | 0.66 | RAB9A (0.97) | ALDH1A1HPGDTSHRL3MBTL1MAPT | |
| SCHEMBL24893103 | 0.66 | AR (0.53) | ALDH1A1L3MBTL1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL31329299 | 0.66 | SMN1; SMN2 (0.64) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL16726972 | 0.65 | GAA (0.46) | ALDH1A1HPGDTSHRKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |