Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sulfurous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 known ✓ | P09917 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | G6PD | P11413 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfurous Acid SCHEMBL8000721 | 1.00 | GAA (0.81) | GAAG6PDL3MBTL1ALOX5 | |
| Sulfurous Acid SCHEMBL8000715 | 0.94 | GAA (0.77) | GAAG6PDL3MBTL1ALOX5 | |
| SCHEMBL2002701 | 0.90 | GAA (1.00) | GAAG6PDL3MBTL1ALOX5 | |
| Phenidone SCHEMBL8386575 | 0.79 | G6PD (0.77) | GAAG6PDL3MBTL1ALOX5 | |
| SCHEMBL456398 | 0.75 | GAA (0.71) | GAAG6PDL3MBTL1ALOX5 | |
| SCHEMBL7094860 | 0.73 | GAA (0.69) | GAAG6PDL3MBTL1ALOX5 | |
| SCHEMBL8751385 | 0.73 | GAA (0.68) | GAAG6PDL3MBTL1ALOX5 | |
| SCHEMBL16906432 | 0.72 | GAA (0.66) | GAAG6PDL3MBTL1 | |
| SCHEMBL13177674 | 0.71 | G6PD (0.66) | GAAG6PDL3MBTL1ALOX5 | |
| SCHEMBL8752194 | 0.71 | GAA (0.66) | GAAG6PDL3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087078-A | LOW SILVER BLACK-AND-WHITE PHOTOGRAPHIC SILVER HALIDE ELEMENTS, SUCH AS RADIOGRAPHIC FILMS, CAN BE PROCESSED QUICKLY USING BLACK-AND-WHITE DEVELOPING AND FIXING COMPOSITONS HAVING REDUCED PHOTOPROCESSING ACTIVITY | EASTMAN KODAK COMPANY (US) | 2000-07-11 | — | — | US | disclosed |